ORGANIC CHEMISTRY II
LABORATORY MANUAL
By
STEPHEN ANDERSON
And
ROBERT SHINE
MAHWAH, NEW
JANUARY 2009
© 2009 STEPHEN ANDERSON
AND ROBERT SHINE
CONTENTS AND SCHEDULE:
LAB
1 CHECK IN, SAFETY AND PROCEDURES
LAB
2 SODIUM BOROHYDRIDE REDUCTION
LAB 3 HYPOCHLORITE OXIDATION - GREEN CHEMISTRY
LAB 4 GRIGNARD REACTION
LAB 5 DIELS ALDER REACTION
LAB 6
NITRATION OF METHYL BENZOATE
LAB 7 FRIEDEL-CRAFTS ALKYLATION
LAB 8 QUALITATIVE ORGANIC ANALYSIS AND SIM-ORG
LAB 9 ALDOL CONDENSATION REACTIONS
LAB
10 WILLIAMSON SYTHESIS
LAB
11 ANALYSIS OF CARBOHYDRATES
LAB
12 HYDROLYSIS OF METHYL BENZOATE -
GREEN METRICS
LAB 13 REVIEW - GREEN METRICS, SIM-ORG AND CHECKOUT
LABORATORY FINAL EXAMINATION
© 2009 STEPHEN ANDERSON AND ROBERT SHINE
ORGANIC CHEMISTRY II
LABORATORY MANUAL
APPENDICES
APPENDIX LIST:
APPENDIX A: QUALITATIVE ORGANIC ANALYSIS AND SIM-ORG
APPENDIX B: SAFETY ISSUES
APPENDIX C: COMMENTS ABOUT WRITING STYLE
APPENDIX D: MEASUREMENTS AND SIGNIFICANT FIGURES
APPENDIX E: PERCENT YIELD CALCULATION METHOD
APPENDIX F: GREEN METRICS
APPENDIX G: CHEMICAL DATA
ACKNOWLEDGEMENTS: The Authors wish to thank the following
people for their assistance with this manual: Carol Ichinco
(Laboratory Coordinator), Thomas Drwiega (Laboratory
Technician), Gurpreet Kaur
(Honors Research Student), Benjamin Barrios (Research Student), and all the
other Instructors who have taught Organic Chemistry Laboratory sections for the
past few years. Dr. Scott Frees and
Jeffrey Ludwig are acknowledged for their work in writing and developing the Sim-Org qualitative organic analysis simulation program.
© 2009 STEPHEN ANDERSON
AND ROBERT SHINE