Important Note:
This course requires several prerequisites. I expect that you have a thorough understanding of fundamentals of Biology & Chemistry, Organic Chemistry and Genetics. To ensure your progress in the class, you are recommended to refresh your memories with topics related to Gene Expression before joining the class. You should be well grounded about the structure of DNA, RNA and Proteins. You should also have in depth knowledge of DNA replication transcription and translation. This information can be found in text books of Genetics and other Biology books. Several websites, including http://gslc.genetics.utah.edu/units/basics/, http://www.roche.com/pages/genedcd6/English/TitleSequence/TitleSeq.html, and http://www.nature.com/scitable/study-center are also useful.
Click on the topic-links below to open the documents containing the lecture-outlines / handouts for the listed topic. You may need a password to open some of the documents. Contact me if you need to know the password. The links will become ALIVE a few days before the scheduled lecture.
You would need Acrobat Reader to open some of the files. Click Here if you want to download free Adobe Acrobat Reader.
Note: The links below might not be in the same order as the lecture schedule. Please look at the lecture syllabus for correct sequence of lectures.
# |
Topic |
| 1. | |
| 2. | The Dynamic Cell: An introduction |
| 3. |
Macromolecules: Storage and Expression of Genetic Information
|
| 4. |
Macromolecules: Protein Structure & Function |
| 5. | Cell Probing Tools: How Cells are Studied |
| 6. |
Bioinformatics, Genomics and Proteomics: Handout Gene Expression on a Genomic Scale: DeRisi et_al 1997.pdf (Self reading assignment) |
| 7. | Membrane Structure |
| 8. | Intracellular Compartments: Nucleus, ER, Peroxisomes and "Protein Sorting" |
| 9. | Receptor Mediated Endocytosis |
| 10. |
Eukaryotic pre-mRNA Processing
|
| 11. |
RNAi
|
| 12. | Cell to Cell Signaling |
| 13. | Cell Division and Regulation of Cell Cycle |
| 14. |
Programmed Cell Death and Apoptosis
|
| 15. | Cancer |
| 16. | The Genetic Basis of Cancer |
| 17. | Role of Carcinogens and DNA Repair in Cancer |
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